Case Report


Clinical case of a giant asymptomatic low-grade appendiceal mucinous neoplasm

1 Chief General Surgery Unit, Mater Olbia Hospital, Olbia, Italy; Dipartimento Scienze Mediche e chirurgiche, Fondazione Policlinico Universitario A. Gemelli, IRCCS di Roma, Largo Agostino Gemelli 8, 00168 Roma, Italy

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Alessandro Verbo

Chief General Surgery Unit, Mater Olbia Hospital, Olbia, Italy; Dipartimento Scienze Mediche e chirurgiche, Fondazione Policlinico Universitario A. Gemelli, IRCCS di Roma, Largo Agostino Gemelli 8, 00168 Roma,

Italy

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Article ID: 100146Z10AV2025

doi: 10.5348/100146Z10AV2025CR

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How to cite this article

Verbo A. Clinical case of a giant asymptomatic low-grade appendiceal mucinous neoplasm. J Case Rep Images Oncology 2025;11(1):33–36.

ABSTRACT


Introduction: Low-grade appendiceal mucinous neoplasms (LAMNs) are rare tumors with nonspecific clinical features. Abdominal computed tomography (CT) is the primary diagnostic tool. Surgical resection is the standard treatment, requiring “en bloc” tumor removal to minimize the risk of rupture. Laparoscopic surgery is a safe and effective approach.

Case Report: A 74-year-old female patient was admitted for evaluation of a pelvic mass. Physical examination revealed a non-tender abdomen with a palpable pelvic mass. Imaging showed significant thickening and dilation of the appendix. Laparoscopic surgery confirmed LAMN. The patient recovered well with no complications at follow-up.

Conclusion: Low-grade appendiceal mucinous neoplasms are rare tumors with variable presentations. Abdominal CT and enteroscopy are crucial for diagnosis. Laparoscopic surgery offers a safe and effective treatment, ensuring favourable outcomes.

Keywords: Case report, Laparoscopic surgery, Low-grade appendiceal mucinous neoplasm, Pseudomyxoma peritonei

SUPPORTING INFORMATION


Author Contributions

Alessandro Verbo - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Author declares no conflict of interest.

Copyright

© 2025 Alessandro Verbo. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.