 |
Case Series
Angiofibroma of soft tissue in the subcutis: A radiologic-pathologic study of three cases
1 Department of Orthopaedic Surgery, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka 540-0006, Japan
Address correspondence to:
Ikuo Kudawara
MD, PhD, Department of Orthopaedic Surgery, National Hospital Organization Osaka National Hospital, 2-1-14 Hoenzaka, Chuo-ku, Osaka 540-0006,
Japan
Message to Corresponding Author
Article ID: 100144Z10IK2025
Access full text article on other devices
Access PDF of article on other devices
How to cite this article
Kudawara I. Angiofibroma of soft tissue in the subcutis: A radiologic-pathologic study of three cases. J Case Rep Images Oncology 2025;11(1):20–24.ABSTRACT
Introduction: Angiofibroma of soft tissue (AFST) in the subcutis is a rare condition with few cases reported in the literature.
Case Series: Three cases of angiofibroma of soft tissue in the subcutis of extremities are presented. Two cases which received surgery have no recurrent tumor for three years and one year, respectively. The remaining case underwent only excisional biopsy and was lost to follow-up.
Conclusion: Radiological features of AFST were commonly well-circumscribed, round or oval configuration with homogeneous intermediate signal intensity on T1-weighted image on magnetic resonance imaging (MRI). The tumors were located in the subcutis of extremities and attached to the fascia or aponeurosis, but histologically no evidence of infiltration. The histopathological features were composed of oval or spindle cells with various degree of the cellularity, small vessels, and collagen fibers or myxoid matrix.
Keywords: Angiofibroma of soft tissue, Magnetic resonance imaging, Pathology, Radiology
SUPPORTING INFORMATION
Acknowledgments
The author thanks Dr. Eiichi Konishi for the histopathological review.
Author ContributionsIkuo Kudawara - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthor declares no conflict of interest.
Copyright© 2025 Ikuo Kudawara. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
