Case Report


A case study of successful percutaneous coronary intervention in a young adult with chronic graft-versus-host disease with acute coronary syndrome

,  ,  ,  ,  ,  

1 Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA

2 Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA

3 Department of Cardiology, Brigham and Women’s Hospital, Boston, MA 02115, USA

Address correspondence to:

Sunakshi Bassi

300 Longwood Ave, Boston, MA 02115,

USA

Message to Corresponding Author


Article ID: 100108Z10SB2022

doi: 10.5348/100108Z10SB2022CR

Access full text article on other devices

Access PDF of article on other devices

How to cite this article

Bassi S, Gearhart A, Liddle D, Shah PB, Hartz J, Esch J. A case study of successful percutaneous coronary intervention in a young adult with chronic graft-versus-host disease with acute coronary syndrome. J Case Rep Images Oncology 2022;8(2):5–9.

ABSTRACT


Introduction: Acute coronary syndrome in pediatric patients with graft-versus-host disease is rare.

Case Report: We present an 18-year-old male with graft-versus-host disease referred for chest pain, electrocardiogram abnormalities, and troponin leak. Additional risk factors for acute coronary syndrome included chronic steroid use, elevated triglyceride/low-density lipoprotein (LDL) levels and cannabis use. A catheterization revealed >90% occlusion of the left coronary artery and he underwent successful percutaneous intervention.

Conclusion: Given the overall rarity of acute coronary syndrome in pediatric patients, it may go unrecognized and underappreciated as a significant cause of morbidity in those with graft-versus-host disease.

Keywords: Acute coronary syndrome, Case report, Graft-versus-host disease, Pediatrics

SUPPORTING INFORMATION


Author Contributions

Sunakshi Bassi - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Addison Gearhart - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

David Liddle - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Pinak B Shah - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Jacob Hartz - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Jesse Esch - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2022 Sunakshi Bassi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.