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Case Report
1 Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
2 Department of Cardiology, Boston Children’s Hospital, Boston, MA 02115, USA
3 Department of Cardiology, Brigham and Women’s Hospital, Boston, MA 02115, USA
Address correspondence to:
Sunakshi Bassi
300 Longwood Ave, Boston, MA 02115,
USA
Message to Corresponding Author
Article ID: 100108Z10SB2022
Introduction: Acute coronary syndrome in pediatric patients with graft-versus-host disease is rare.
Case Report: We present an 18-year-old male with graft-versus-host disease referred for chest pain, electrocardiogram abnormalities, and troponin leak. Additional risk factors for acute coronary syndrome included chronic steroid use, elevated triglyceride/low-density lipoprotein (LDL) levels and cannabis use. A catheterization revealed >90% occlusion of the left coronary artery and he underwent successful percutaneous intervention.
Conclusion: Given the overall rarity of acute coronary syndrome in pediatric patients, it may go unrecognized and underappreciated as a significant cause of morbidity in those with graft-versus-host disease.
Keywords: Acute coronary syndrome, Case report, Graft-versus-host disease, Pediatrics
Sunakshi Bassi - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Addison Gearhart - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
David Liddle - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Pinak B Shah - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jacob Hartz - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jesse Esch - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Sunakshi Bassi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.