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Case Report
Posterior reversible encephalopathy syndrome in a patient with hematopoietic stem cell transplant (HSCT)-associated thrombotic microangiopathy (TA-TMA)
1 DO, Resident, Internal Medicine, San Antonio Uniformed Services Health Consortium, San Antonio, TX, USA
2 MD, San Antonio Uniformed Services Health Consortium; Staff Attending, Hematology-Oncology, San Antonio, TX, USA
Address correspondence to:
Kristin E Stoll
San Antonio Uniformed Services Health Consortium, Brooke Army Medical Center, 500 Roger Brooke Drive, San Antonio, TX 78234,
USA
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Article ID: 100085Z10KS2021
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How to cite this article
Stoll KE, Lee L. Posterior reversible encephalopathy syndrome in a patient with hematopoietic stem cell transplant (HSCT)-associated thrombotic microangiopathy (TA-TMA). J Case Rep Images Oncology 2021;7:100085Z10KS2021.ABSTRACT
Hematopoietic stem cell transplant (HSCT)-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication of transplantation and is associated with significant morbidity. We describe a unique case of TA-TMA associated with Streptococcus pyogenes bacteremia and posterior reversible encephalopathy syndrome (PRES) in a patient with a history of aplastic anemia who experienced complete neurologic recovery after plasma exchange and Eculizumab. This case highlights the importance of early recognition and treatment of TA-TMA and contributes to the reported cases of such occurrence.
Keywords: Posterior reversible encephalopathy syndrome; Transplant-associated thrombotic microangiopathy
SUPPORTING INFORMATION
Author Contributions
Kristin E Stoll - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Lauren Lee - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 Kristin E Stoll et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
