Case Report


Common cancer, puzzling presentation: A report of endometrial cancer presenting as an obstructive duodenal mass

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1 Cleveland Clinic Women’s Health Institute, Department of OBGYN, Cleveland, Ohio, USA

2 Cleveland Clinic Women’s Health Institute, Division of Gynecologic Oncology, Cleveland, Ohio, USA

3 Cleveland Clinic, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland, Ohio, USA

Address correspondence to:

Ji Son

MD, MS, 9500 Euclid Ave, Desk A81, Cleveland, Ohio 44195,

USA

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Article ID: 100067Z10JS2020

doi: 10.5348/100067Z10JS2020CR

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How to cite this article

Son J, Das D, Connor E, Pannunzio A, Michener CM. Common cancer, puzzling presentation: A report of endometrial cancer presenting as an obstructive duodenal mass. J Case Rep Images Oncology 2020;6:100067Z10JS2020.

ABSTRACT


The risk of extrauterine spread in endometrial cancer depends on the histologic type and grade. Metastatic endometrial cancer typically follows a predictable pattern of spread, favoring the lymphatic route. We report an unusual case of a patient with International Federation of Gynecology and Obstetrics (FIGO) grade 2 endometrioid endometrial cancer who presented with an obstructive duodenal mass with no other preoperative evidence of disease. Available diagnostic data suggested a possible second primary cancer. Upon entering the abdomen, it became apparent that the duodenal mass was a metastatic focus. The final pathology revealed a high-grade serous component. Underestimation of endometrial biopsy, failure of diagnostic imaging, and the nonspecificity of fine needle aspiration led to diagnostic difficulty. Staging laparoscopy may be useful in such cases.

Keywords: Duodenal mass, Metastatic endometrial cancer, Staging laparoscopy

SUPPORTING INFORMATION


Author Contributions

Ji Son - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Deepanjana Das - Acquisition of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Elizabeth Connor - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Andrea Pannunzio - Acquisition of data, Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published

Chad M Michener - Substantial contributions to conception and design, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Because the patient is now deceased, written informed consent was obtained from the patient’s next-of-kin, her husband, for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2020 Ji Son et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.