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Case Report
Lentiform fork sign: A distinctive neuroradiologic manifestation of uremic encephalopathy—A case report
1 Consultant Radiologist, Department of Radiology, King Abdulla Hospital, Bisha, Kingdom of Saudi Arabia
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Khalid Mohamed Abdalla
Department of Radiology, King Abdulla Hospital, Bisha,
Kingdom of Saudi Arabia
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Article ID: 101476Z01AM2024
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Mbaba AN, Abdalla KM, Ahmed HM. Lentiform fork sign: A distinctive neuroradiologic manifestation of uremic encephalopathy—A case report. Int J Case Rep Images 2024;15(2):81–84.ABSTRACT
Introduction: The lentiform fork sign is a unique magnetic resonance imaging (MRI) appearance of the basal ganglia believed to be due to acute metabolic acidosis and seen in several conditions that result in metabolic acidosis such as uremic encephalopathy.
Case Report: We present the case of a 76-year-old hypertensive and diabetic male patient with end-stage renal failure on dialysis, whose brain MRI revealed bilateral symmetrical T2W and fluid-attenuated inversion recovery hyperintensities in the basal ganglia, surrounded by a hyperintense rim delineating the lentiform nuclei, giving rise to the lentiform fork sign.
Conclusion: We describe this under-reported unique sign, the lentiform fork sign, in an end-stage renal disease patient, whose brain MRI revealed this sign to highlight the significance of this sign, which has been widely reported to be associated with uremic encephalopathy.
Keywords: Basal ganglia hyperintensity, Lentiform fork sign, MRI, Uremic encephalopathy
SUPPORTING INFORMATION
Author Contributions
Awajimijan Nathaniel Mbaba - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Khalid Mohamed Abdalla - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Hamza Mustapha Ahmed - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Awajimijan Nathaniel Mbaba et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
