Case Report


Highlights of serious distant effects after local injection of botulinum toxin therapy: A report of pediatric case

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1 Assistant Professor of Clinical Toxicology-Poison Control Center, Department of Forensic Medicine & Clinical Toxicology, Faculty of Medicine, Ain Shams University, Cairo, Egypt

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Hoda M Salah Eldin

Department of Forensic Medicine & Clinical Toxicology, Faculty of Medicine, Ain Shams University, Cairo,

Egypt

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Article ID: 101127Z01EM2020

doi: 10.5348/101127Z01EM2020CR

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How to cite this article

Mohammed EA, Salah Eldin HM. Highlights of serious distant effects after local injection of botulinum toxin therapy: A report of pediatric case. Int J Case Rep Images 2020;11:101127Z01EM2020.

ABSTRACT


Introduction: Botulinum neurotoxin A (BoNT-A) is widely used in various conditions that cause involuntary muscle contractions, such as management of spasticity in cerebral palsy (CP). However, iatrogenic botulism resulting from systemic effects from BoNT-A is uncommon but may have serious life-threatening consequences.

Case Report: We report a case of pediatric patient who developed iatrogenic botulism after therapeutic intramuscular injections of BoNT-A.

Conclusion: This case highlights the importance of clinicians having adequate information of the risk of systemic botulism following local injections of BoNT-A and caution is needed in using this therapy.

Keywords: Botulinum neurotoxin A, Iatrogenic botulism

SUPPORTING INFORMATION


Author Contributions

Eman Abdelfatah Mohammed - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Hoda M Salah Eldin - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2020 Eman Abdelfatah Mohammed et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.