Case Report


A case of primary squamous cell carcinoma of the parotid gland and review of the literature

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1 School of Stomatology, Shanxi Medical University, Taiyuan, Shanxi, China

2 Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Taiyuan, Shanxi, China

3 First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

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Xinrong Nan

First Hospital of Shanxi Medical University, Taiyuan, Shanxi,

China

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Article ID: 100128Z10JZ2024

doi: 10.5348/100128Z10JZ2024CR

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How to cite this article

Zhao J, Nan X, Zhou C, Jiang N, Tian L. A case of primary squamous cell carcinoma of the parotid gland and review of the literature. J Case Rep Images Oncology 2024;10(1):7–12.

ABSTRACT


Introduction: Primary parotid squamous cell carcinoma (PPSCC) is a rare malignant epithelial tumor originating in the parotid gland with complex diagnostic procedures and a poor prognosis. The etiology, tissue origin, and biological behavior of the disease are currently unknown due to its underreporting. It is crucial to differentiate this type of squamous cell carcinoma (SCC) of the parotid gland from other salivary gland tumors because of its widespread invasiveness, which leads to high mortality.

Case Report: This article reports a case of a 62-year-old male patient in whom histopathological examination confirmed that the tumor was squamous cell carcinoma. Since the patient had no other main source, the ultimate diagnosis was the primary SCC of the parotid gland. The patient is currently receiving routine follow-up care and has shown no signs of recurrence.

Conclusion: In conclusion, even asymptomatic individuals should be highly regarded to prevent mistakes because the diagnostic process for this disease is complicated. The presence of metastatic cancer should be ruled out, and histology and immunohistochemistry should be used to confirm the diagnosis.

Keywords: Fine-needle aspiration cytology, Parotid gland, Parotid squamous cell carcinoma, Primary squamous cell carcinoma

SUPPORTING INFORMATION


Author Contributions

Jingli Zhao - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Xinrong Nan - Revising it critically for important intellectual content, Final approval of the version to be published

Chuhuan Zhou - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published

Nan Jiang - Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published

Liangliang Tian - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2024 Jingli Zhao et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.