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Case Report
Composite lymphoma of the axillary lymph node comprising peripheral T-cell lymphoma-not otherwise specified and follicular B-cell lymphoma: A case report
1 Hazard ARH Regional Medical Center, Hazard, KY, USA
2 Lincoln Memorial University-DeBusk College of Osteopathic Medicine, Harrogate, TN, USA
3 East Tennessee State University, Johnson City, TN, USA
Address correspondence to:
Joshua K Jenkins
P.O. Box 558, Hazard, KY 41702,
USA
Message to Corresponding Author
Article ID: 100106Z10SK2022
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Kolagatla S, Jenkins JK, Fatima Z, Chaudhary S, Moka N. Composite lymphoma of the axillary lymph node comprising peripheral T-cell lymphoma-not otherwise specified and follicular B-cell lymphoma: A case report. J Case Rep Images Oncology 2022;8(1):15–20.ABSTRACT
Introduction: Composite lymphoma is defined as coexistence of two or more morphologically and phenotypically distinct lymphomas in the same anatomical site. Composite lymphoma may include combinations of Hodgkin lymphoma (HL) and B- or T-cell non-Hodgkin lymphoma (NHL); B-cell NHL and T-cell NHL; or two distinct B-cell or T-cell NHLs. The exact pathogenesis of composite lymphoma is unknown. Most cases demonstrate poor outcomes with a median survival of 12 months. The treatment is usually directed toward the higher-grade component.
Case Report: Here, we report an extraordinarily rare case of a composite lymphoma composed of peripheral T-cell lymphoma-not otherwise specified (PTCL-NOS) and follicular B-cell lymphoma (FBCL) coexisting in a single axillary lymph node in a 66-year-old female.
Conclusion: The medical literature lacks significant information regarding this type of composite lymphoma, thus creating a challenge for management. Currently, only one other case of this type of composite lymphoma has been reported in the English medical literature, with this case reporting the first female patient.
Keywords: Composite lymphoma, Follicular lymphoma, Peripheral T-cell lymphoma
SUPPORTING INFORMATION
Author Contributions
Sandhya Kolagatla - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Joshua K Jenkins - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Zainab Fatima - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Shweta Chaudhary - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Nagabhishek Moka - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Sandhya Kolagatla et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
