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Case Report
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| Acute pancreatitis induced by cisplatin-etoposide regimen | ||||||
| Abdulqadir J. Nashwan1, Hind H. Elmalik2, Sindhumole L. K. Nair1, Mohamed A. Yassin3 | ||||||
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1Nurse Educator, Hamad Medical Corporation – Nurse Educator, Department of Nursing Education & Research, National Center for Cancer Care and Research (NCCCR), Doha, Qatar.
2Oncology Consultant, Hamad Medical Corporation – Oncology Consultant, Department of Medical Oncology, National Center for Cancer Care and Research (NCCCR), Doha, Qatar. 3Hematology Consultant, Hamad Medical Corporation – Hematology Consultant, Department of Hematology and BMT, National Center for Cancer Care and Research (NCCCR), Doha, Qatar. | ||||||
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| How to cite this article: |
| Nashwan AJ, Elmalik HH, Nair SLK, Yassin MA. Acute pancreatitis induced by cisplatin-etoposide regimen. J Case Rep Images Oncology 2016;2:61–65. |
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Abstract
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Introduction:
Drug-induced pancreatitis is less prevalent compared to other causes of acute pancreatitis, the incidence ranges between 0.1–2% of acute pancreatitis. Several reports are suggesting the association of pancreatitis with cisplatin but etoposide has not been reported to associate with pancreatitis.
Case Report: A 25-year-old, Filipino lady presented with Stage IV cervical cancer with neuroendocrine features. She was started on chemotherapy regimen of cisplatin and etoposide. She tolerated the six cycles of chemotherapy, and she was planned to start concurrent chemoradiation. However, due to persistently elevated levels of serum creatinine, she could not receive cisplatin. During radiotherapy, she has developed acute pancreatitis. The common causes of acute pancreatitis were ruled out; given the time course, it was assumed that the chemotherapeutic agents; cisplatin and etoposide might be suggested risk factors for the development of pancreatitis in our patient. Conclusion: Early identification of acute pancreatitis helps in instituting effective treatment. Therefore, knowledge regarding acute pancreatitis related to cisplatin has utmost significance. | |
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Keywords:
Acute Pancreatitis, Cisplatin, Etoposide, Neuroendocrine cervical cancer
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Author Contributions
Abdulqadir J. Nashwan – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Hind H. Elmalik – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Sindhumole L. K. Nair – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published Mohamed A. Yassin – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published |
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Guarantor of submission
The corresponding author is the guarantor of submission. |
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Source of support
None |
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Conflict of interest
Authors declare no conflict of interest. |
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Copyright
© 2016 Abdulqadir J. Nashwan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information. |
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About The Authors
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